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A Mechanism of Gene Amplification Driven by Small DNA Fragments

DNA amplification is a molecular process that increases the copy number of a chromosomal tract and often causes elevated expression of the amplified gene(s). Although gene amplification is frequently observed in cancer and other degenerative disorders, the molecular mechanisms involved in the proces...

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Detalhes bibliográficos
Main Authors: Mukherjee, Kuntal, Storici, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521702/
https://ncbi.nlm.nih.gov/pubmed/23271978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003119
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