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Taxol-stabilized microtubules promote the formation of filaments from unmodified full-length Tau in vitro

Tau is a neuronal protein that stabilizes the microtubule (MT) network, but it also forms filaments associated with Alzheimer's disease. Understanding Tau–MT and Tau–Tau interactions would help to establish Tau function in health and disease. For many years, literature reports on Tau–MT binding...

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Autors principals: Duan, Aranda R., Goodson, Holly V.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521687/
https://ncbi.nlm.nih.gov/pubmed/23087208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0374
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