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Tuning Promoter Strength through RNA Polymerase Binding Site Design in Escherichia coli

One of the paramount goals of synthetic biology is to have the ability to tune transcriptional networks to targeted levels of expression at will. As a step in that direction, we have constructed a set of [Image: see text] unique binding sites for E. coli RNA Polymerase (RNAP) [Image: see text] holoe...

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Autori principali: Brewster, Robert C., Jones, Daniel L., Phillips, Rob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521663/
https://ncbi.nlm.nih.gov/pubmed/23271961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002811
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