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Reduced MTHFD1 Activity in Male Mice Perturbs Folate- and Choline-Dependent One-Carbon Metabolism as Well as Transsulfuration(1)(2)

Impaired utilization of folate is caused by insufficient dietary intake and/or genetic variation and has been shown to prompt changes in related pathways, including choline and methionine metabolism. These pathways have been shown to be sensitive to variation within the Mthfd1 gene, which codes for...

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Detalhes bibliográficos
Main Authors: Field, Martha S., Shields, Kelsey S., Abarinov, Elena V., Malysheva, Olga V., Allen, Robert H., Stabler, Sally P., Ash, Jessica A., Strupp, Barbara J., Stover, Patrick J., Caudill, Marie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521460/
https://ncbi.nlm.nih.gov/pubmed/23190757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.112.169821
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