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Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice(1)(2)(3)(4)(5)

Background: Low dietary choline intake has been proposed to increase the risk of neural tube defects (NTDs) in human populations. Mice with reduced Shmt1 expression exhibit a higher frequency of NTDs when placed on a folate- and choline-deficient diet and may represent a model of human NTDs. The ind...

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Главные авторы: Beaudin, Anna E, Abarinov, Elena V, Malysheva, Olga, Perry, Cheryll A, Caudill, Marie, Stover, Patrick J
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Nutrition 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238454/
https://ncbi.nlm.nih.gov/pubmed/22134951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.111.020305
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