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Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice(1)(2)(3)(4)(5)
Background: Low dietary choline intake has been proposed to increase the risk of neural tube defects (NTDs) in human populations. Mice with reduced Shmt1 expression exhibit a higher frequency of NTDs when placed on a folate- and choline-deficient diet and may represent a model of human NTDs. The ind...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Nutrition
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238454/ https://ncbi.nlm.nih.gov/pubmed/22134951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.111.020305 |
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