MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline(1)(2)(3)

Background: Homozygosity for the variant 677T allele in the methylenetetrahydrofolate reductase (MTHFR) gene increases the requirement for folate and may alter the metabolic use of choline. The choline adequate intake is 550 mg/d for men, although the metabolic consequences of consuming extra cholin...

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Bibliografiske detaljer
Main Authors: Yan, Jian, Wang, Wei, Gregory, Jesse F, Malysheva, Olga, Brenna, J Thomas, Stabler, Sally P, Allen, Robert H, Caudill, Marie A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Nutrition 2011
Fag:
Vitamins, Minerals, and Phytochemicals
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021427/
https://ncbi.nlm.nih.gov/pubmed/21123458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.110.005975
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