Construction of Opa-Positive and Opa-Negative Strains of Neisseria meningitidis to Evaluate a Novel Meningococcal Vaccine

Neisseria meningitidis is a major global pathogen causing invasive disease with a mortality of 5–10%. Most disease in developed countries is caused by serogroup B infection, against which there is no universal vaccine. Opacity-associated adhesin (Opa) proteins are major meningococcal outer membrane...

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Main Authors: Sadarangani, Manish, Hoe, J. Claire, Callaghan, Martin J., Jones, Claire, Chan, Hannah, Makepeace, Katherine, Daniels-Treffandier, Hélène, Deadman, Mary E., Bayliss, Christopher, Feavers, Ian, van der Ley, Peter, Pollard, Andrew J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521020/
https://ncbi.nlm.nih.gov/pubmed/23251421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051045
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