Activation of Invariant NKT Cells with Glycolipid Ligand α-Galactosylceramide Ameliorates Glucose-6-Phosphate Isomerase Peptide-Induced Arthritis

OBJECTIVE: Invariant natural killer T (iNKT) cells regulate collagen-induced arthritis (CIA) when activated by their potent glycolipid ligand, alpha-galactosylceramide (α-GalCer). Glucose-6-phosphate isomerase (GPI)-induced arthritis is a closer model of human rheumatoid arthritis based on its assoc...

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Autori principali: Horikoshi, Masanobu, Goto, Daisuke, Segawa, Seiji, Yoshiga, Yohei, Iwanami, Keiichi, Inoue, Asuka, Tanaka, Yuki, Matsumoto, Isao, Sumida, Takayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520964/
https://ncbi.nlm.nih.gov/pubmed/23251456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051215
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