Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis

INTRODUCTION: Immunization with glucose-6-phosphate isomerase (GPI) induces severe arthritis in DBA/1 mice. The present study was designed to identify the cytokines and co-stimulatory molecules involved in the development of GPI-induced arthritis. METHODS: Arthritis was induced in DBA/1 mice with 30...

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Main Authors: Matsumoto, Isao, Zhang, Hua, Yasukochi, Takanori, Iwanami, Keiichi, Tanaka, Yoko, Inoue, Asuka, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumida, Takayuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483457/
https://ncbi.nlm.nih.gov/pubmed/18534002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2437
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