Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis

INTRODUCTION: Arthritis induced by immunisation with glucose-6-phosphate isomerase (GPI) in DBA/1 mice was proven to be T helper (Th) 17 dependent. We undertook this study to identify GPI-specific T cell epitopes in DBA/1 mice (H-2q) and investigate the mechanisms of arthritis generation. METHODS: F...

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Hauptverfasser: Iwanami, Keiichi, Matsumoto, Isao, Tanaka, Yoko, Inoue, Asuka, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumida, Takayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656230/
https://ncbi.nlm.nih.gov/pubmed/18992137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2545
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