Activation of natural killer T cells by α-carba-GalCer (RCAI-56), a novel synthetic glycolipid ligand, suppresses murine collagen-induced arthritis

Alpha-carba-GalCer (RCAI-56), a novel synthetic analogue of α-galactosylceramide (α-GalCer), stimulates invariant natural killer T (NK T) cells to produce interferon (IFN)-γ. IFN-γ exhibits immunoregulatory properties in autoimmune diseases by suppressing T helper (Th)-17 cell differentiation and in...

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Detalles Bibliográficos
Main Authors: Yoshiga, Y, Goto, D, Segawa, S, Horikoshi, M, Hayashi, T, Matsumoto, I, Ito, S, Taniguchi, M, Sumida, T
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2011
Assuntos:
Animal Models
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087916/
https://ncbi.nlm.nih.gov/pubmed/21391989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04369.x
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