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Discrete Kinetic Models from Funneled Energy Landscape Simulations

A general method for facilitating the interpretation of computer simulations of protein folding with minimally frustrated energy landscapes is detailed and applied to a designed ankyrin repeat protein (4ANK). In the method, groups of residues are assigned to foldons and these foldons are used to map...

詳細記述

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書誌詳細
主要な著者: Schafer, Nicholas P., Hoffman, Ryan M. B., Burger, Anat, Craig, Patricio O., Komives, Elizabeth A., Wolynes, Peter G.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520928/
https://ncbi.nlm.nih.gov/pubmed/23251375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050635
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