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Prediction of Native State Hydrogen Exchange from Perfectly Funneled Energy Landscapes

Simulations based on perfectly funneled energy landscapes often capture many of the kinetic features of protein folding. We examined whether simulations based on funneled energy functions can also describe fluctuations in native state protein ensembles. We quantitatively compared the site-specific l...

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Detalhes bibliográficos
Main Authors: Craig, Patricio O., Lätzer, Joachim, Weinkam, Patrick, Hoffman, Ryan M.B., Ferreiro, Diego U., Komives, Elizabeth A., Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203634/
https://ncbi.nlm.nih.gov/pubmed/21913704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja207506z
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