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A funneled energy landscape for cytochrome c directly predicts the sequential folding route inferred from hydrogen exchange experiments
Proteins fold through a variety of mechanisms. For a given protein, folding routes largely depend on the protein's stability and its native-state geometry, because the landscape is funneled. These ideas are corroborated for cytochrome c by using a coarse-grained topology-based model with a perf...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1194935/ https://ncbi.nlm.nih.gov/pubmed/16116080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505274102 |
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