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Funneling and frustration in the energy landscapes of some designed and simplified proteins

We explore the similarities and differences between the energy landscapes of proteins that have been selected by nature and those of some proteins designed by humans. Natural proteins have evolved to function as well as fold, and this is a source of energetic frustration. The sequence of Top7, on th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Truong, Ha H., Kim, Bobby L., Schafer, Nicholas P., Wolynes, Peter G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AIP Publishing LLC 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732306/
https://ncbi.nlm.nih.gov/pubmed/24089720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4813504
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