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Funneling and frustration in the energy landscapes of some designed and simplified proteins
We explore the similarities and differences between the energy landscapes of proteins that have been selected by nature and those of some proteins designed by humans. Natural proteins have evolved to function as well as fold, and this is a source of energetic frustration. The sequence of Top7, on th...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
AIP Publishing LLC
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732306/ https://ncbi.nlm.nih.gov/pubmed/24089720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4813504 |
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