Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Sporadic canine colorectal cancers (CRCs) should make excellent models for studying the corresponding human cancers. To molecularly characterize canine CRC, we investigated exonic sequence mutations of adenomatous polyposis coli (APC), the best known tumor suppressor gene of human CRC, in 23 sporadi...

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Detalhes bibliográficos
Main Authors: Youmans, Lydia, Taylor, Cynthia, Shin, Edwin, Harrell, Adrienne, Ellis, Angela E., Séguin, Bernard, Ji, Xinglai, Zhao, Shaying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519478/
https://ncbi.nlm.nih.gov/pubmed/23251390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050813
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