Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors

Sporadic canine colorectal cancers (CRCs) should make excellent models for studying the corresponding human cancers. To molecularly characterize canine CRC, we investigated exonic sequence mutations of adenomatous polyposis coli (APC), the best known tumor suppressor gene of human CRC, in 23 sporadi...

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Détails bibliographiques
Auteurs principaux: Youmans, Lydia, Taylor, Cynthia, Shin, Edwin, Harrell, Adrienne, Ellis, Angela E., Séguin, Bernard, Ji, Xinglai, Zhao, Shaying
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519478/
https://ncbi.nlm.nih.gov/pubmed/23251390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050813
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