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The Survival Motor Neuron protein forms soluble glycine zipper oligomers
The Survival Motor Neuron (SMN) protein forms the oligomeric core of a multi-protein complex that functions in spliceosomal snRNP biogenesis. Loss of function mutations in the SMN gene cause spinal muscular atrophy (SMA), a leading genetic cause of infant mortality. Nearly half of the known SMA pati...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519385/ https://ncbi.nlm.nih.gov/pubmed/23022347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.024 |
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