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Oligomeric Properties of Survival Motor Neuron·Gemin2 Complexes
The survival motor neuron (SMN) protein forms the oligomeric core of a multiprotein complex required for the assembly of spliceosomal small nuclear ribonucleoproteins. Deletions and mutations in the SMN1 gene are associated with spinal muscular atrophy (SMA), a devastating neurodegenerative disease...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536428/ https://ncbi.nlm.nih.gov/pubmed/26092730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.667279 |
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