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Oligomeric Properties of Survival Motor Neuron·Gemin2 Complexes

The survival motor neuron (SMN) protein forms the oligomeric core of a multiprotein complex required for the assembly of spliceosomal small nuclear ribonucleoproteins. Deletions and mutations in the SMN1 gene are associated with spinal muscular atrophy (SMA), a devastating neurodegenerative disease...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Gupta, Kushol, Martin, Renee, Sharp, Robert, Sarachan, Kathryn L., Ninan, Nisha S., Van Duyne, Gregory D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536428/
https://ncbi.nlm.nih.gov/pubmed/26092730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.667279
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