Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer

Protein oligomerization is one mechanism by which homogenous solutions can separate into distinct liquid phases, enabling assembly of membraneless organelles. Survival Motor Neuron (SMN) is the eponymous component of a large macromolecular complex that chaperones biogenesis of eukaryotic ribonucleop...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gupta, Kushol, Wen, Ying, Ninan, Nisha S, Raimer, Amanda C, Sharp, Robert, Spring, Ashlyn M, Sarachan, Kathryn L, Johnson, Meghan C, Van Duyne, Gregory D, Matera, A Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287954/
https://ncbi.nlm.nih.gov/pubmed/34181727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab508
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