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Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

Patients with cancer have an impaired T cell response that can decrease the potential therapeutic benefit of cancer vaccines and other forms of immunotherapy. The establishment of a chronic inflammatory environment in patients with cancer plays a critical role in the induction of T cell dysfunction....

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Autors principals: Raber, Patrick, Ochoa, Augusto C., Rodríguez, Paulo C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519282/
https://ncbi.nlm.nih.gov/pubmed/23017138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08820139.2012.680634
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