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Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells

Regulatory T (Treg) cells are essential in preventing the host from developing certain autoimmune diseases and limiting excessive immune responses against pathogens. The normal function of most Treg cells requires sustained expression of functional FOXP3, a member of the FOXP family transcription fa...

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Detalhes bibliográficos
Main Authors: Deng, Guoping, Xiao, Yan, Zhou, Zhaocai, Nagai, Yasuhiro, Zhang, Hongtao, Li, Bin, Greene, Mark I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518637/
https://ncbi.nlm.nih.gov/pubmed/23041265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.013
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