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Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells

Regulatory T (Treg) cells are essential in preventing the host from developing certain autoimmune diseases and limiting excessive immune responses against pathogens. The normal function of most Treg cells requires sustained expression of functional FOXP3, a member of the FOXP family transcription fa...

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Autors principals: Deng, Guoping, Xiao, Yan, Zhou, Zhaocai, Nagai, Yasuhiro, Zhang, Hongtao, Li, Bin, Greene, Mark I.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518637/
https://ncbi.nlm.nih.gov/pubmed/23041265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.09.013
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