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The lupus-prone NZM2410/NZW strain derived Sle1b sub-locus alters the germinal center checkpoint in female mice in a B cell intrinsic manner
C57BL/6 (B6) mice carrying the Sle1b sub-locus (named B6.Sle1b), which harbors the lupus-associated NZM2410/NZW SLAM family genes, produce anti-nuclear antibodies (ANA). However, the role and mechanism(s) involved in the alteration of the germinal center (GC) tolerance checkpoint in the development...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518623/ https://ncbi.nlm.nih.gov/pubmed/23144494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201661 |
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