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Selective blockade of BAFF prevents and treats SLE nephritis in NZM2410 mice

OBJECTIVES: To determine whether BAFF or combined BAFF/APRIL blockade is effective in a mouse model of SLE nephritis characterized by rapidly progressive glomerulosclerosis. METHODS: NZM2410 mice at early and late stages of disease were treated with a short course of BAFF-R-Ig or TACI-Ig. Mice were...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ramanujam, Meera, Bethunaickan, Ramalingam, Huang, Weiqing, Tao, Haiou, Madaio, Michael P., Davidson, Anne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917190/
https://ncbi.nlm.nih.gov/pubmed/20131293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27368
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