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Selective blockade of BAFF prevents and treats SLE nephritis in NZM2410 mice
OBJECTIVES: To determine whether BAFF or combined BAFF/APRIL blockade is effective in a mouse model of SLE nephritis characterized by rapidly progressive glomerulosclerosis. METHODS: NZM2410 mice at early and late stages of disease were treated with a short course of BAFF-R-Ig or TACI-Ig. Mice were...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917190/ https://ncbi.nlm.nih.gov/pubmed/20131293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27368 |
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