Selective blockade of BAFF prevents and treats SLE nephritis in NZM2410 mice

OBJECTIVES: To determine whether BAFF or combined BAFF/APRIL blockade is effective in a mouse model of SLE nephritis characterized by rapidly progressive glomerulosclerosis. METHODS: NZM2410 mice at early and late stages of disease were treated with a short course of BAFF-R-Ig or TACI-Ig. Mice were...

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Sonraí Bibleagrafaíochta
Main Authors: Ramanujam, Meera, Bethunaickan, Ramalingam, Huang, Weiqing, Tao, Haiou, Madaio, Michael P., Davidson, Anne
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917190/
https://ncbi.nlm.nih.gov/pubmed/20131293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27368
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