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IFNα CONFERS RESISTANCE OF SLE NEPHRITIS TO THERAPY IN NZB/WF1 MICE

The critical role of IFNα in the pathogenesis of human systemic lupus erythematosus (SLE) has been highlighted in recent years. Exposure of young lupus-prone NZB/W F1 mice to IFNα in vivo leads to an accelerated lupus phenotype that is dependent on T cells and is associated with elevated serum level...

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Detalhes bibliográficos
Main Authors: Liu, Zheng, Bethunaickan, Ramalingam, Huang, Weiqing, Ramanujam, Meera, Madaio, Michael P., Davidson, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140572/
https://ncbi.nlm.nih.gov/pubmed/21705616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004142
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