Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex

The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein translocation are not well understood. The str...

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Hlavní autoři: Whitehouse, Sarah, Gold, Vicki A.M., Robson, Alice, Allen, William J., Sessions, Richard B., Collinson, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518217/
https://ncbi.nlm.nih.gov/pubmed/23209305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205191
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