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The dynamic action of SecA during the initiation of protein translocation

The motor ATPase SecA drives protein secretion through the bacterial Sec complex. The PPXD (pre-protein cross-linking domain) of the enzyme has been observed in different positions, effectively opening and closing a clamp for the polypeptide substrate. We set out to explore the implicated dynamic ro...

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Autori principali: Gold, Vicki A. M., Whitehouse, Sarah, Robson, Alice, Collinson, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685266/
https://ncbi.nlm.nih.gov/pubmed/23126322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121314
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