Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex

The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein translocation are not well understood. The str...

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Main Authors: Whitehouse, Sarah, Gold, Vicki A.M., Robson, Alice, Allen, William J., Sessions, Richard B., Collinson, Ian
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2012
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518217/
https://ncbi.nlm.nih.gov/pubmed/23209305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205191
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