Constitutively active phosphodiesterase activity regulates urinary bladder smooth muscle function: critical role of K(Ca)1.1 channel

Pharmacological blockade of cyclic nucleotide phosphodiesterase (PDE) can relax human urinary bladder smooth muscle (UBSM); however, the underlying cellular mechanism is unknown. In this study, we investigated the effects of PDE pharmacological blockade on human UBSM excitability, spontaneous and ne...

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Detalhes bibliográficos
Main Authors: Xin, Wenkuan, Cheng, Qiuping, Soder, Rupal P., Rovner, Eric S., Petkov, Georgi V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518192/
https://ncbi.nlm.nih.gov/pubmed/22896041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00351.2012
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