Molecular Characterization of EGFR and EGFRvIII Signaling Networks in Human Glioblastoma Tumor Xenografts

Glioblastoma multiforme (GBM) is a malignant primary brain tumor with a mean survival of 15 months with the current standard of care. Genetic profiling efforts have identified the amplification, overexpression, and mutation of the wild-type (wt) epidermal growth factor receptor tyrosine kinase (EGFR...

Full description

Saved in:
Bibliographic Details
Main Authors: Johnson, Hannah, Del Rosario, Amanda M., Bryson, Bryan D., Schroeder, Mark A., Sarkaria, Jann N., White, Forest M.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518138/
https://ncbi.nlm.nih.gov/pubmed/22964225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.019984
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items