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Viral Diversity Threshold for Adaptive Immunity in Prokaryotes

Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas). CRISPR-Cas systems are genomic sensors that se...

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Detalles Bibliográficos
Main Authors: Weinberger, Ariel D., Wolf, Yuri I., Lobkovsky, Alexander E., Gilmore, Michael S., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517865/
https://ncbi.nlm.nih.gov/pubmed/23221803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00456-12
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