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Solvent Exposure Associated with Single Abasic Sites Alters the Base Sequence-Dependence of Oxidation of Guanine in DNA in GG Sequence Contexts
The effect of exposure of guanine in double-stranded oligonucleotides to aqueous solvent on its oxidation by one-electron oxidants was investigated by introducing single synthetic tetrahydrofuran-type abasic site (Ab) either adjacent to or opposite tandem GG sequences. The selective oxidation of gua...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517150/ https://ncbi.nlm.nih.gov/pubmed/21656632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100140 |
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