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NKG2A is a marker for acquisition of regulatory function by human CD8+ T cells activated with anti-CD3 antibody
Treatment with anti-CD3 mAbs modulates immune responses that cause Type 1 diabetes and other diseases. CD8+ Tregs can be induced in vitro and in vivo by the mAb. However, 1/3 of patients do not respond to drug therapy and in an equal proportion, anti-CD3 mAb does not induce Tregs in vitro. The acqui...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517122/ https://ncbi.nlm.nih.gov/pubmed/21538351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041258 |
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