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Enhanced Anti-Serpin Antibody Activity Inhibits Autoimmune Inflammation in Type 1 Diabetes

Intracellular (clade B) ovalbumin (ov)-serpin protease inhibitors play an important role in tissue homeostasis by protecting cells from death in response to hypoosmotic stress, heat shock and other stimuli. Whether these serpins influence immunological tolerance and the risk for autoimmune diseases...

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Hlavní autoři: Czyzyk, Jan, Henegariu, Octavian, Preston-Hurlburt, Paula, Baldzizhar, Raman, Fedorchuk, Christine, Esplugles, Enric, Bottomly, Kim, Gorus, Frans K., Herold, Kevan, Flavell, Richard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370061/
https://ncbi.nlm.nih.gov/pubmed/22593614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200467
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