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Analysis of FcR non-binding anti-CD3 mAb in humanized mice identifies novel human gut tropic cells with regulatory function that are found in patients

The development and optimization of immune therapies in patients has been hampered by the lack of preclinical models in which their effects on human immune cells can be studied. As a result, observations that have been made in preclinical studies have suggested mechanisms of drug action in murine mo...

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Detalhes bibliográficos
Main Authors: Waldron-Lynch, Frank, Henegariu, Octavian, Deng, Songyan, Preston-Hurlburt, Paula, Tooley, James, Flavell, Richard, Herold, Kevan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131554/
https://ncbi.nlm.nih.gov/pubmed/22277969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003401
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