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NKG2A is a marker for acquisition of regulatory function by human CD8+ T cells activated with anti-CD3 antibody

Treatment with anti-CD3 mAbs modulates immune responses that cause Type 1 diabetes and other diseases. CD8+ Tregs can be induced in vitro and in vivo by the mAb. However, 1/3 of patients do not respond to drug therapy and in an equal proportion, anti-CD3 mAb does not induce Tregs in vitro. The acqui...

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Autors principals: Ablamunits, Vitaly, Henegariu, Octavian, Preston-Hurlburt, Paula, Herold, Kevan C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517122/
https://ncbi.nlm.nih.gov/pubmed/21538351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041258
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