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Atom-Economic and Stereoselective Syntheses of the A- and B-Ring Subunits of the Bryostatins

This article describes chemoselective and atom-economical methods for the stereoselective assembly of the A- and B-ring subunits of the bryostatins. A Ru-catalyzed tandem alkene-alkyne coupling/Michael addition was developed and applied to the synthesis of the bryostatin B-ring. We explored an acety...

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Detalhes bibliográficos
Main Authors: Trost, Barry M., Yang, Hanbiao, Brindle, Cheyenne S., Dong, Guangbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517072/
https://ncbi.nlm.nih.gov/pubmed/21774000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002930
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