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Total Synthesis of Bryostatins. Development of Methodology for Atom-Economic and Stereoselective Synthesis of the C-ring Subunit

Bryostatins, a family of structurally complicated macrolides, exhibit an exceptional range of biological activities. The limited availability and structural complexity of these molecules makes development of an efficient total synthesis particularly important. This article describes our initial effo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Trost, Barry M., Frontier, Alison J., Thiel, Oliver R., Yang, Hanbiao, Dong, Guangbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437499/
https://ncbi.nlm.nih.gov/pubmed/21793057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002898
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