The Cytosolic GH Loop Regulates the Phosphatidylinositol 4,5-Bisphosphate-induced Gating Kinetics of Kir2 Channels

Inwardly rectifying K(+) (Kir) channels set the resting membrane potential and regulate cellular excitability. The activity of Kir channels depends critically on the phospholipid PIP(2). The molecular mechanism by which PIP(2) regulates Kir channel gating is poorly understood. Here, we utilized a co...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: An, Hai-Long, Lü, Shou-Qin, Li, Jun-Wei, Meng, Xuan-Yu, Zhan, Yong, Cui, Meng, Long, Mian, Zhang, Hai-Lin, Logothetis, Diomedes E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516771/
https://ncbi.nlm.nih.gov/pubmed/23033482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418640
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker