Identification of Amino Acid Residues Required for the Substrate Specificity of Human and Mouse Chondroitin Sulfate Hydrolase (Conventional Hyaluronidase-4)

Human hyaluronidase-4 (hHYAL4), a member of the hyaluronidase family, has no hyaluronidase activity, but is a chondroitin sulfate (CS)-specific endo-β-N-acetylgalactosaminidase. The expression of hHYAL4 is not ubiquitous but restricted to placenta, skeletal muscle, and testis, suggesting that hHYAL4...

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Main Authors: Kaneiwa, Tomoyuki, Miyazaki, Anzu, Kogawa, Ryo, Mizumoto, Shuji, Sugahara, Kazuyuki, Yamada, Shuhei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Glycobiology and Extracellular Matrices
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516757/
https://ncbi.nlm.nih.gov/pubmed/23086929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360693
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