Subunit-specific Incorporation Efficiency and Kinetics in Mitochondrial Complex I Homeostasis

Studies employing native PAGE suggest that most nDNA-encoded CI subunits form subassemblies before assembling into holo-CI. In addition, in vitro evidence suggests that some subunits can directly exchange in holo-CI. Presently, data on the kinetics of these two incorporation modes for individual CI...

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Main Authors: Dieteren, Cindy E. J., Koopman, Werner J. H., Swarts, Herman G., Peters, Janny G. P., Maczuga, Piotr, van Gemst, Jasper J., Masereeuw, Rosalinde, Smeitink, Jan A. M., Nijtmans, Leo G. J., Willems, Peter H. G. M.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
主題:
Protein Synthesis and Degradation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516733/
https://ncbi.nlm.nih.gov/pubmed/23038253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.391151
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