Subunit-specific Incorporation Efficiency and Kinetics in Mitochondrial Complex I Homeostasis

Studies employing native PAGE suggest that most nDNA-encoded CI subunits form subassemblies before assembling into holo-CI. In addition, in vitro evidence suggests that some subunits can directly exchange in holo-CI. Presently, data on the kinetics of these two incorporation modes for individual CI...

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Detalhes bibliográficos
Main Authors: Dieteren, Cindy E. J., Koopman, Werner J. H., Swarts, Herman G., Peters, Janny G. P., Maczuga, Piotr, van Gemst, Jasper J., Masereeuw, Rosalinde, Smeitink, Jan A. M., Nijtmans, Leo G. J., Willems, Peter H. G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516733/
https://ncbi.nlm.nih.gov/pubmed/23038253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.391151
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