Subunits of Mitochondrial Complex I Exist as Part of Matrix- and Membrane-associated Subcomplexes in Living Cells

Mitochondrial complex I (CI) is a large assembly of 45 different subunits, and defects in its biogenesis are the most frequent cause of mitochondrial disorders. In vitro evidence suggests a stepwise assembly process involving pre-assembled modules. However, whether these modules also exist in vivo i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dieteren, Cindy E. J., Willems, Peter H. G. M., Vogel, Rutger O., Swarts, Herman G., Fransen, Jack, Roepman, Ronald, Crienen, Gijs, Smeitink, Jan A. M., Nijtmans, Leo G. J., Koopman, Werner J. H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Membrane Transport, Structure, Function, and Biogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259887/
https://ncbi.nlm.nih.gov/pubmed/18826940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807323200
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