Dual Regulation of Diacylglycerol Kinase (DGK)-θ: POLYBASIC PROTEINS PROMOTE ACTIVATION BY PHOSPHOLIPIDS AND INCREASE SUBSTRATE AFFINITY

Diacylglycerol kinases are important mediators of lipid signaling cascades, and insight into their regulation is of increasing interest. Using purified DGK-θ, we show that this isoform is subject to dual regulation and that the previously characterized stimulation by acidic phospholipids is dependen...

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Bibliografiska uppgifter
Huvudupphovsmän: Tu-Sekine, Becky, Raben, Daniel M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Enzymology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516713/
https://ncbi.nlm.nih.gov/pubmed/23091060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404855
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