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Dual Regulation of Diacylglycerol Kinase (DGK)-θ: POLYBASIC PROTEINS PROMOTE ACTIVATION BY PHOSPHOLIPIDS AND INCREASE SUBSTRATE AFFINITY

Diacylglycerol kinases are important mediators of lipid signaling cascades, and insight into their regulation is of increasing interest. Using purified DGK-θ, we show that this isoform is subject to dual regulation and that the previously characterized stimulation by acidic phospholipids is dependen...

詳細記述

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書誌詳細
主要な著者: Tu-Sekine, Becky, Raben, Daniel M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516713/
https://ncbi.nlm.nih.gov/pubmed/23091060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404855
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