Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

Human genetic variation is distributed nonrandomly across the genome, though the principles governing its distribution are only partially known. DNA replication creates opportunities for mutation, and the timing of DNA replication correlates with the density of SNPs across the human genome. To enabl...

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Bibliografiske detaljer
Main Authors:	Koren, Amnon, Polak, Paz, Nemesh, James, Michaelson, Jacob J., Sebat, Jonathan, Sunyaev, Shamil R., McCarroll, Steven A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2012
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3516607/ https://ncbi.nlm.nih.gov/pubmed/23176822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.10.018
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Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

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