A Novel Test for Gene-Ancestry Interactions in Genome-Wide Association Data

Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific effects, via interactions on genetic background or w...

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Bibliographic Details
Main Authors: Davies, Joanna L., Cazier, Jean-Baptiste, Dunlop, Malcolm G., Houlston, Richard S., Tomlinson, Ian P., Holmes, Chris C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516524/
https://ncbi.nlm.nih.gov/pubmed/23236349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048687
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