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Leveraging local ancestry to detect gene-gene interactions in genome-wide data

BACKGROUND: Although genome-wide association studies have successfully identified thousands of variants associated to complex traits, these variants only explain a small amount of the entire heritability of the trait. Gene-gene interactions have been proposed as a source to explain a significant per...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Aschard, Hugues, Gusev, Alexander, Brown, Robert, Pasaniuc, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619349/
https://ncbi.nlm.nih.gov/pubmed/26498930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0283-z
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