Clustering by genetic ancestry using genome-wide SNP data

BACKGROUND: Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest....

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Detalhes bibliográficos
Main Authors: Solovieff, Nadia, Hartley, Stephen W, Baldwin, Clinton T, Perls, Thomas T, Steinberg, Martin H, Sebastiani, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018397/
https://ncbi.nlm.nih.gov/pubmed/21143920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-108
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